The RAGS study is part of a program of ongoing surveillance of licensed vaccines.
The main objectives of the RAGS study are:
- To assess the effectiveness of Rotavirus vaccine (given to babies as part of the routine immunization schedule). This is done by looking at children with gastroenteritis symptoms in the Princess Margaret Hospital emergency department and those who are admitted to hospital.
- To determine the impact the Rotavirus vaccine has on Rotavirus strains circulating in the community.
Vaccine Trials Group is recruiting children up to 5 years of age who have had at least 3 diarrhoea episodes within a 24 hour period.
Research staff collect samples when the child is in hospital and later contact the parents to inform them of the results as well as asking them when their child's diarrhoea and vomiting stopped.
RAGS is a five year study that commenced in 2010.
Vaccine Trials Group aims to recruit 1000 subjects averaging 200 recruits per year.